The body adapts its oxygen distribution through allostery

Hemoglobin is a protein whose affinity for dioxygen varies according to the chemical environment of red blood cells. When glycolysis accelerates, 2,3-bisphosphoglycerate accumulates and signals the molecule to release more gas to the tissues. An acidic pH causes the same release of oxygen through a phenomenon named the Bohr effect, discovered by the physiologist of the same name.