Caravaggio draws inspiration from a 15th-century work

Caravaggio draws inspiration from the Sacrifice of Isaac imagined by Filippo Brunelleschi two centuries earlier. This theme had given rise to a fierce competition between Brunelleschi and Lorenzo Ghiberti at the beginning of the 15th century for the Florence Baptistery. Caravaggio abandons the elegant composition of Ghiberti in favor of the more violent vision of Brunelleschi.